Berberine HCL

Dihydroberberine - Plant Extract Powder
Specifications97% Berberine HCl (HPLC)
Botanical SourceBerberis aristata
TrademarkEarayberine
OriginChina
StandardUSP / EP / Enterprise Standard
EfficacySupports glucose metabolism, cardiovascular health, gut microbiome balance
CAS No.633-65-8
AppearanceYellow crystalline powder

Berberine HCl is a quaternary ammonium salt extracted from the roots, rhizomes and stem bark of Berberis aristata and other Berberis species. As a high-purity alkaloid standardized to 97% by HPLC, Earayberine offers consistent potency for nutraceutical and pharmaceutical applications.

Modern research has identified berberine's role in activating AMPK (adenosine monophosphate-activated protein kinase), often referred to as a metabolic master switch. This mechanism supports healthy glucose uptake, lipid metabolism, and cellular energy balance.

Assay (Berberine HCl)97% min HPLC
AppearanceYellow crystalline powder
Loss on Drying5.0% max
Residue on Ignition0.5% max
Heavy Metals (Pb)10 ppm max
Arsenic (As)2 ppm max
Total Plate Count1,000 cfu/g max
Yeast & Mold100 cfu/g max
  1. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008;57(5):712-717.
  2. Kong W, et al. Berberine is a novel cholesterol-lowering drug. Nat Med. 2004;10(12):1344-1351.
  3. Zhang H, et al. Berberine improves glucose metabolism. J Clin Invest. 2004.